05/12/2019 / By Michelle Simmons
People with diabetes have a higher risk of complications, including cardiovascular disease. In a new study, researchers from Greece found that daily supplementation with alpha-lipoic acid (ALA), carnosine, and thiamine not only lowers blood sugar levels but also fights oxidative stress and inhibit platelet aggregation to provide better cardiovascular protection.
Published in the Journal of Medicinal Food, the study looked at the effectiveness of an individualized oral supplementation with ALA, carnosine, and thiamine in obese individuals with Type 2 diabetes. To do this, the researchers recruited 82 obese individuals with Type 2 diabetes and divided them into two groups: a treatment group and a control group. Participants in the treatment group received 7 milligrams per kilogram body weight (mg/kg) of ALA, 6 mg/kg of carnosine, and 1 mg/kg of thiamine every day for eight weeks, while those in the control group received a placebo.
Moreover, the researchers measured the participants’ oxidative stress levels and platelet aggregation at the beginning and the end of the study. They also examined the antiplatelet activity of each of the supplement’s components ex vivo at human and washed rabbit platelets.
The results of the study revealed that daily intake of ALA, carnosine, and thiamine supplements led to reductions in blood sugar and oxidative stress levels. In addition, the supplementation reduced insulin sensitivity but increased insulin levels. It also reduced platelet aggregation, but the researchers identified that ALA was the only inhibitor of platelet aggregation. From these findings, the researchers concluded that daily supplementation with ALA, carnosine, and thiamine exhibit blood sugar-lowering, antioxidant, and cardioprotective effects in obese patients with Type 2 diabetes.
In addition to ALA, carnosine, and thiamine, there are other herbs and supplements that people with Type 2 diabetes may find beneficial. These include:
Visit SupplementsReport.com to learn more about other supplements beneficial to people with Type 2 diabetes.
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ALA, alpha-lipoic acid, blood sugar, cardiovascular health, carnosine, diabetes, diabetes science, obese, obesity, prevention, research, supplements, thiamine, Type 2 Diabetes, vitamin b1
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